SUGGESTED USE: 2 capsules per day or as recommended by your health care professional.

A Natural Supplement for Eye Health and Vision Support

The eye is the most susceptible organ to oxidative damage. 4 Sight is nutritional support for individuals wanting to increase the intake of specific ocular antioxidants in order to maintain optimal eye health and vision support.

4 Sight provides excellent support for those who want to maintain eye health, and also for those with age-related antioxidant issues. Developed in conjunction with a nationally known Ophthalmologist, 4 Sight was "in the trenches" giving support to those who needed it, long before age-related antioxidant issues made the headlines with such great media exposure. Ingredients used in 4 Sight are of the utmost quality, ensuring you the proper support your eyes deserve. Many of the ingredients included in 4 Sight, such as lycopene and lutein, have been used in studies for their role in supporting eye health.

The Role of Antioxidants in Eye Health

Antioxidants play a large role in eye health. Oxidative damage is one of the primary causes of poor eye health, including macular degeneration and cataract formation. In a recent study done on AREDS (Age-Related Eye Disease), it was shown that supplementation with betacarotene (15 mg), vitamin C (500 mg), vitamin E (400 IU), zinc (80 mg), plus copper (2 mg) had a beneficial effect on the progression to age-related macular degeneration (AMD). Another clinical trial is currently looking at the effects lutein and zeaxanthin with or without DHA and EPA have on the progression to advanced age-related macular degeneration.

4 Sight Supplement Includes These Natural Ingredients:

•Quercetin and Eye Health
Quercetin is a flavonoid which has a high biological activity and is used as a potent antioxidant. Quercetin is found widely in the plant kingdom, including in onions. In vitro, Quercetin has been shown to inhibit human lens aldose reductase (an enzyme that converts glucose to sorbitol). Sorbitol cannot be transported through the lens membrane and therefore accumulates in the lens tissue, causing damage.

•N-Acetyl L-Cysteine (NAC) for Eye Health
N-Acetyl L-Cysteine is another antioxidant and is also a precursor to the antioxidant glutathione. Glutathione concentrations in the eye are very high when compared to other tissues in the body, low levels are associated with poor eye health. Oral glutathione is not well absorbed in the body, supplementing with NAC may be a better way to achieve optimal glutathione levels.

•Ginkgo Biloba Extract and Eye Health
Ginkgo Biloba has historically been used to increase circulation, and while its use in retinal protection is less popular there are a few studies that show its benefits. In one study, ginkgo was able to protect retinas from damage induced by different enzymes and xenobiotics.

•Natural Bilberry Extract (Vaccinium Myrtillus)
Bilberry extract contains high amounts of flavinoid antioxidants called anthocyanosides. These unique antioxidants have been known to improve night vision by expediting the production of rhodopsin (a purple pigment sensitive to red light found in the retinal rods of the eyes). Bilberry extracts have historically been used to improve night vision. Extracts of bilberry are widely used in France and Germany for vascular conditions (such as strengthening capillaries, stabilizing collagen, maintaining structural integrity of arterial walls and preventing the excessive clustering of platelets) as well as night vision support.

•Zinc for Eye Health and Vision Support
Zinc is an essential trace mineral and carries many important roles in the human body and is necessary for maintaining optimal eye health. Zinc is a key ingredient in over 50 different proteins and enzymes, one being superoxide dismutase (SOD). Superoxide dismutase is vital to the quenching of free radicals in the lens and retina. Zinc is also used in other antioxidant enzymes including catalase. Studies have shown that zinc is able to significantly reduce visual loss when compared to placebo.

•Taurine for Proper Vision and Eye Health
Taurine is an amino acid made by the body. Retinal concentrations of taurine are quite high and taurine is also required for the proper development of the retinal tissues. Taurine has been shown to be able to stimulate the replication of human retinal pigmented epithelial cells.

•Carotenoids (Lutein, Lycopene, Zeaxanthin)
Lutein and zeaxanthin are found in high concentrations in the macula lutea portion of the eye. These two carotenoids are thought to quench free-radicals before they damage the lipid membranes. Studies have shown that lutein and zeaxanthin increase macular pigment and lower the risk of age-related macular degeneration (AMD). Low levels of lycopene, one of 10 carotenoids found in the serum, has also been shown to be a risk factor for poor eye health.

•Lipoic Acid and Eye Health
Lipoic Acid, once known as thioctic acid, is considered one of the most versatile antioxidants. Lipoic acid is able to recharge the antioxidants vitamin E, ascorbic acid (vitamin C), and glutathione. Lipoic acid has also been shown to inhibit the activity of aldose reductase in hyperglycaemic conditions and improve visual function in a study of glaucoma patients.

CONTRAINDICATIONS:
Caution is advised for those taking blood thinning medications. If you are pregnant or nursing consult your physican. Diabetic patients should talk with their physician about any changes in medications due to potential changes in blood sugar control.

These statements have not been evaluated by the FDA. This product is not intended to treat, diagnose, prevent, or cure any disease. Consult a physician before taking. Should you experience any serious physical side effects from taking these nutritional supplements, discontinue and call your doctor immediately.